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BAY 73-1449

CAS No. 693790-96-4

BAY 73-1449 ( BAY73-1449; BAY 73-1449 )

产品货号. M27855 CAS No. 693790-96-4

BAY 73-1449 is a selective and potent antagonist of the prostacyclin receptor(IC50<0.1 nM).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥2001 有现货
10MG ¥3345 有现货
25MG ¥5605 有现货
50MG ¥7979 有现货
100MG ¥10773 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    BAY 73-1449
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    BAY 73-1449 is a selective and potent antagonist of the prostacyclin receptor(IC50<0.1 nM).
  • 产品描述
    BAY 73-1449 is a selective and potent antagonist of the prostacyclin receptor(IC50<0.1 nM).(In Vivo):In male Wistar rats, BAY 73-1449 (0.1-1 mg/kg; i.v.) significantly reduced splenic shunt vessel outflow without affecting mesenteric inflow. BAY 73-1449 (1-5 mg/kg; s.c.) has no effects on portal pressures and the degree of porto-systemic shunting in rats.
  • 同义词
    BAY73-1449; BAY 73-1449
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    RhoA; Lbc
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    693790-96-4
  • 分子量
    425.5
  • 分子式
    C26H23N3O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    OC(=O)[C@H](Cc1ccccc1)Nc1cc(ncn1)-c1ccc(OCc2ccccc2)cc1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Francesca FANELLI, et al. Compounds and composition for use in the inhibition of the lbc-rhoa interaction, in particular for the treatment of cancer. WO2015028929A1.
产品手册
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